NM_007294.4(BRCA1):c.5558dup (p.Tyr1853Ter)
Source
ClinVar variation 55628: NM_007294.4(BRCA1):c.5558dup (p.Tyr1853Ter)
Recipes that this example satisfies
Properties
id: clinvar:55628ClinVar Variation ID, where 55628 is the Variation ID listed within the Identifiers section of ClinVar’s Variant Details.
type: CategoricalVariantThis value is required by the specification for all Categorical Variant objects.
name: NM_007294.4(BRCA1):c.5558dup (p.Tyr1853Ter)Human-readable label listed within the Identifiers section of ClinVar’s Variant Details.
description: A brief placeholder note.This field was populated with an example value because ClinVar does not contain a longform description of this variant.
aliases: A subset of HGVS representationsA subset of HGVS representations from ClinVar’s Variant Details, including the MANE Select nucleotide coding (NM_007294.4:c.5558dup) and protein expressions (NP_009225.1:p.Tyr1853Ter and NP_009225.1:p.Y1853*), the full HGVS name with single-letter amino acid abbreviation, and both GRCh38 and GRCh37 hgvs.g variants, as well as the Canonical SPDI representation provided by ClinVar.
extensions: cytogenetic location, clinvar variation type, and hgvs listThe cytogenetic location (17q21.31) and ClinVar variation type (Duplication) are obtained from ClinVar’s Variant Details. The hgvs list extension includes GRCh38 genomic, GRCh37 genomic, MANE Select coding, and protein HGVS representations.
mappings: ClinVar, ClinGen, and dbSNPMappings to ClinVar’s page for the variant, ClinGen, and dbSNP are included from the Links section of ClinVar’s Variant Details.
Constraints
- Defining Allele Constraint
The
allelefield is populated with the VRS Allele corresponding to the MANE Select protein representation NP_009225.1:p.Tyr1853Ter, as included withinmembers. The constraint includes a translation_of relation linking the protein allele to its coding DNA representation.
Members
The members field includes three VRS Allele objects generated using the VICC Variation Normalizer:
NC_000017.11:g.43045712dup (GRCh38 genomic, on refseq:NC_000017.11)
NC_000017.10:g.41197729dup (GRCh37 genomic, on refseq:NC_000017.10)
NP_009225.1:p.Tyr1853Ter (protein, on the MANE Select protein product for BRCA1 refseq:NP_009225.1)
The variant normalization service was unable to generate a VRS Allele for the MANE Select coding representation NM_007294.4:c.5558dup.
Full example: JSON
{
"id": "clinvar:55628",
"type": "CategoricalVariant",
"name": "NM_007294.4(BRCA1):c.5558dup (p.Tyr1853Ter)",
"description": "An example categorical variant that models NM_007294.4(BRCA1):c.5558dup (p.Tyr1853Ter) from ClinVar.",
"aliases": [
"NM_007294.4:c.5558dup",
"NP_009225.1:p.Tyr1853Ter",
"NP_009225.1:p.Y1853*",
"NM_007294.4(BRCA1):c.5558dup (p.Y1853*)",
"NC_000017.11:g.43045712dup",
"NC_000017.10:g.41197729dup",
"NC_000017.11:43045711:T:TT"
],
"extensions": [
{
"name": "cytogenetic location",
"value": "17q21.31"
},
{
"name": "clinvar variation type",
"value": "Duplication"
},
{
"name": "hgvs list",
"value": [
{
"nucleotideExpression": {
"syntax": "hgvs.g",
"value": "NC_000017.11:g.43045712dup"
},
"nucleotideType": "genomic"
},
{
"nucleotideExpression": {
"syntax": "hgvs.g",
"value": "NC_000017.10:g.41197729dup"
},
"nucleotideType": "genomic"
},
{
"nucleotideExpression": {
"syntax": "hgvs.c",
"value": "NM_007294.4:c.5558dup"
},
"nucleotideType": "coding",
"maneSelect": true,
"proteinExpression": {
"syntax": "hgvs.p",
"value": "NP_009225.1:p.Tyr1853Ter"
},
"molecularConsequence": {
"name": "stop_gained",
"system": "http://www.sequenceontology.org/browser/",
"systemVersion": "release_2.5.3",
"code": "SO:0001587",
"iris": [
"http://www.sequenceontology.org/browser/release_2.5.3/term/SO:0001587"
]
}
}
]
}
],
"constraints": [
{
"type": "DefiningAlleleConstraint",
"allele": {
"id": "ga4gh:VA.BfZ-RbjStWkafMsFBcoSL0f4aAjHJU4n",
"type": "Allele",
"name": "NP_009225.1:p.Tyr1853Ter",
"description": "VRS variation of NP_009225.1:p.Tyr1853Ter, generated with the VICC Variation Normalizer (https://github.com/cancervariants/variation-normalization).",
"digest": "BfZ-RbjStWkafMsFBcoSL0f4aAjHJU4n",
"expressions": [
{
"syntax": "hgvs.g",
"value": "NC_000017.11:g.43045712dup"
},
{
"syntax": "hgvs.g",
"value": "NC_000017.10:g.41197729dup"
},
{
"syntax": "hgvs.c",
"value": "NM_007294.4:c.5558dup"
},
{
"syntax": "hgvs.p",
"value": "NP_009225.1:p.Tyr1853Ter"
}
],
"location": {
"id": "ga4gh:SL.bR3EOtSngkb9wNbixylsw0sNa_2HCga5",
"description": "Amino acid position 1853 of the Refseq protein NP_009225.1, which is the protein product of the MANE Select (GRCh38) coding transcript for BRCA1 (refseq:NM_007294.4).",
"type": "SequenceLocation",
"digest": "bR3EOtSngkb9wNbixylsw0sNa_2HCga5",
"sequenceReference": {
"id": "refseq:NP_009225.1",
"name": "NP_009225.1",
"description": "The protein product of the MANE Select (GRCh38) coding transcript for BRCA1 (refseq:NM_007294.4), corresponding to the Refseq protein accession NP_009225.1.",
"aliases": [
"ensembl:ENSP00000350283.3",
"ga4gh:SQ.nUzIPnHMyQV52hzgBbKl5vlbSwx8M8_Y"
],
"type": "SequenceReference",
"refgetAccession": "SQ.nUzIPnHMyQV52hzgBbKl5vlbSwx8M8_Y",
"residueAlphabet": "aa"
},
"start": 1852,
"end": 1853,
"sequence": "Y"
},
"state": {
"type": "LiteralSequenceExpression",
"sequence": "*"
}
},
"relations": [
{
"primaryCoding": {
"code": "translation_of",
"system": "http://www.sequenceontology.org",
"iris": [
"http://www.sequenceontology.org/browser/current_release/term/translation_of"
]
}
}
]
}
],
"mappings": [
{
"coding": {
"system": "https://www.ncbi.nlm.nih.gov/clinvar",
"code": "55628",
"iris": [
"https://www.ncbi.nlm.nih.gov/clinvar/variation/55628/"
]
},
"relation": "exactMatch"
},
{
"coding": {
"system": "https://reg.clinicalgenome.org/",
"code": "CA003713",
"iris": [
"https://reg.clinicalgenome.org/redmine/projects/registry/genboree_registry/by_caid?caid=CA003713"
]
},
"relation": "relatedMatch"
},
{
"coding": {
"system": "https://www.ncbi.nlm.nih.gov/snp",
"code": "rs80357629",
"iris": [
"https://www.ncbi.nlm.nih.gov/snp/rs80357629"
]
},
"relation": "relatedMatch"
}
],
"members": [
{
"id": "ga4gh:VA.ju31SHNY7xeTI244BcOS7J78dIek46xL",
"type": "Allele",
"name": "NC_000017.11:g.43045712dup",
"description": "VRS variation of NC_000017.11:g.43045712dup, generated with the VICC Variation Normalizer (https://github.com/cancervariants/variation-normalization).",
"digest": "ju31SHNY7xeTI244BcOS7J78dIek46xL",
"expressions": [
{
"syntax": "hgvs.g",
"value": "NC_000017.11:g.43045712dup"
},
{
"syntax": "hgvs.g",
"value": "NC_000017.10:g.41197729dup"
},
{
"syntax": "hgvs.c",
"value": "NM_007294.4:c.5558dup"
},
{
"syntax": "hgvs.p",
"value": "NP_009225.1:p.Tyr1853Ter"
}
],
"location": {
"id": "ga4gh:SL.El1CbTY3p0rvxxkf5qI3YdgTo46YIjwl",
"description": "Genomic position 43,045,712 on chromosome 17 (refseq:NC_000017.11, GRCh38).",
"type": "SequenceLocation",
"extensions": [
{
"name": "GRCh38 1-based, genomic position",
"value": "chr17:43045712",
"description": "Genomic position 43,045,712 on chromosome 17 (refseq:NC_000017.11, GRCh38)."
},
{
"name": "GRCh38 1-based, inclusive interval notation",
"value": "chr17:43045712-43045712",
"description": "Genomic positions 43,045,712 to 43,045,712 on chromosome 17 (refseq:NC_000017.11, GRCh38); 1-based, inclusive interval notation."
},
{
"name": "GRCh38 0-based, half-open interval notation",
"value": "chr17:43045711-43045712",
"description": "Genomic positions 43,045,711 to 43,045,712 on chromosome 17 (refseq:NC_000017.11, GRCh38); 0-based, half-open interval notation."
}
],
"digest": "El1CbTY3p0rvxxkf5qI3YdgTo46YIjwl",
"sequenceReference": {
"id": "refseq:NC_000017.11",
"name": "NC_000017.11",
"description": "Reference sequence for GRCh38 chromosome 17",
"type": "SequenceReference",
"refgetAccession": "SQ.dLZ15tNO1Ur0IcGjwc3Sdi_0A6Yf4zm7",
"residueAlphabet": "na"
},
"start": 43045711,
"end": 43045712,
"sequence": "T"
},
"state": {
"type": "ReferenceLengthExpression",
"length": 2,
"sequence": "TT",
"repeatSubunitLength": 1
}
},
{
"id": "ga4gh:VA.UPNFCFuk1_6v7IzYbbQTV_PsYJ9WOwSa",
"type": "Allele",
"name": "NC_000017.10:g.41197729dup",
"description": "VRS variation of NC_000017.10:g.41197729dup, generated with the VICC Variation Normalizer (https://github.com/cancervariants/variation-normalization).",
"digest": "UPNFCFuk1_6v7IzYbbQTV_PsYJ9WOwSa",
"expressions": [
{
"syntax": "hgvs.g",
"value": "NC_000017.11:g.43045712dup"
},
{
"syntax": "hgvs.g",
"value": "NC_000017.10:g.41197729dup"
},
{
"syntax": "hgvs.c",
"value": "NM_007294.4:c.5558dup"
},
{
"syntax": "hgvs.p",
"value": "NP_009225.1:p.Tyr1853Ter"
}
],
"location": {
"id": "ga4gh:SL.bJxQ_soqGHGy4skIMKp6VLEB54XH32M8",
"description": "Genomic position 41,197,729 on chromosome 17 (refseq:NC_000017.10, GRCh37).",
"type": "SequenceLocation",
"extensions": [
{
"name": "GRCh37 1-based, genomic position",
"value": "chr17:41197729",
"description": "Genomic position 41,197,729 on chromosome 17 (refseq:NC_000017.10, GRCh37)."
},
{
"name": "GRCh37 1-based, inclusive interval notation",
"value": "chr17:41197729-41197729",
"description": "Genomic position 41,197,729 to 41,197,729 on chromosome 17 (refseq:NC_000017.10, GRCh37); 1-based, inclusive interval notation."
},
{
"name": "GRCh37 0-based, half-open interval notation",
"value": "chr17:41197728-41197729",
"description": "Genomic position 41,197,728 to 41,197,729 on chromosome 17 (refseq:NC_000017.10, GRCh37); 0-based, half-open interval notation."
}
],
"digest": "bJxQ_soqGHGy4skIMKp6VLEB54XH32M8",
"sequenceReference": {
"id": "refseq:NC_000017.10",
"name": "NC_000017.10",
"description": "Reference sequence for GRCh37 chromosome 17.",
"aliases": [
"GRCh37:17",
"GRCh37:chr17",
"ga4gh:SQ.AjWXsI7AkTK35XW9pgd3UbjpC3MAevlz"
],
"type": "SequenceReference",
"refgetAccession": "SQ.AjWXsI7AkTK35XW9pgd3UbjpC3MAevlz",
"residueAlphabet": "na"
},
"start": 41197728,
"end": 41197729,
"sequence": "T"
},
"state": {
"type": "ReferenceLengthExpression",
"length": 2,
"sequence": "TT",
"repeatSubunitLength": 1
}
},
{
"id": "ga4gh:VA.BfZ-RbjStWkafMsFBcoSL0f4aAjHJU4n",
"type": "Allele",
"name": "NP_009225.1:p.Tyr1853Ter",
"description": "VRS variation of NP_009225.1:p.Tyr1853Ter, generated with the VICC Variation Normalizer (https://github.com/cancervariants/variation-normalization).",
"digest": "BfZ-RbjStWkafMsFBcoSL0f4aAjHJU4n",
"expressions": [
{
"syntax": "hgvs.g",
"value": "NC_000017.11:g.43045712dup"
},
{
"syntax": "hgvs.g",
"value": "NC_000017.10:g.41197729dup"
},
{
"syntax": "hgvs.c",
"value": "NM_007294.4:c.5558dup"
},
{
"syntax": "hgvs.p",
"value": "NP_009225.1:p.Tyr1853Ter"
}
],
"location": {
"id": "ga4gh:SL.bR3EOtSngkb9wNbixylsw0sNa_2HCga5",
"description": "Amino acid position 1853 of the Refseq protein NP_009225.1, which is the protein product of the MANE Select (GRCh38) coding transcript for BRCA1 (refseq:NM_007294.4).",
"type": "SequenceLocation",
"digest": "bR3EOtSngkb9wNbixylsw0sNa_2HCga5",
"sequenceReference": {
"id": "refseq:NP_009225.1",
"name": "NP_009225.1",
"description": "The protein product of the MANE Select (GRCh38) coding transcript for BRCA1 (refseq:NM_007294.4), corresponding to the Refseq protein accession NP_009225.1.",
"aliases": [
"ensembl:ENSP00000350283.3",
"ga4gh:SQ.nUzIPnHMyQV52hzgBbKl5vlbSwx8M8_Y"
],
"type": "SequenceReference",
"refgetAccession": "SQ.nUzIPnHMyQV52hzgBbKl5vlbSwx8M8_Y",
"residueAlphabet": "aa"
},
"start": 1852,
"end": 1853,
"sequence": "Y"
},
"state": {
"type": "LiteralSequenceExpression",
"sequence": "*"
}
}
]
}
Full example: YAML
id: clinvar:55628
type: CategoricalVariant
name: NM_007294.4(BRCA1):c.5558dup (p.Tyr1853Ter)
description: An example categorical variant that models NM_007294.4(BRCA1):c.5558dup (p.Tyr1853Ter) from ClinVar.
aliases:
- NM_007294.4:c.5558dup
- NP_009225.1:p.Tyr1853Ter
- NP_009225.1:p.Y1853*
- NM_007294.4(BRCA1):c.5558dup (p.Y1853*)
- NC_000017.11:g.43045712dup
- NC_000017.10:g.41197729dup
- NC_000017.11:43045711:T:TT
extensions:
- name: cytogenetic location
value: 17q21.31
- name: clinvar variation type
value: Duplication
- name: hgvs list
value:
- nucleotideExpression:
syntax: hgvs.g
value: NC_000017.11:g.43045712dup
nucleotideType: genomic
- nucleotideExpression:
syntax: hgvs.g
value: NC_000017.10:g.41197729dup
nucleotideType: genomic
- nucleotideExpression:
syntax: hgvs.c
value: NM_007294.4:c.5558dup
nucleotideType: coding
maneSelect: true
proteinExpression:
syntax: hgvs.p
value: NP_009225.1:p.Tyr1853Ter
molecularConsequence:
name: stop_gained
system: http://www.sequenceontology.org/browser/
systemVersion: release_2.5.3
code: SO:0001587
iris:
- http://www.sequenceontology.org/browser/release_2.5.3/term/SO:0001587
constraints:
- type: DefiningAlleleConstraint
allele:
id: ga4gh:VA.BfZ-RbjStWkafMsFBcoSL0f4aAjHJU4n
type: Allele
name: NP_009225.1:p.Tyr1853Ter
description: VRS variation of NP_009225.1:p.Tyr1853Ter, generated with the VICC Variation Normalizer (https://github.com/cancervariants/variation-normalization).
digest: BfZ-RbjStWkafMsFBcoSL0f4aAjHJU4n
expressions:
- syntax: hgvs.g
value: NC_000017.11:g.43045712dup
- syntax: hgvs.g
value: NC_000017.10:g.41197729dup
- syntax: hgvs.c
value: NM_007294.4:c.5558dup
- syntax: hgvs.p
value: NP_009225.1:p.Tyr1853Ter
location:
id: ga4gh:SL.bR3EOtSngkb9wNbixylsw0sNa_2HCga5
description: Amino acid position 1853 of the Refseq protein NP_009225.1, which is the protein product of the MANE Select (GRCh38) coding transcript for BRCA1 (refseq:NM_007294.4).
type: SequenceLocation
digest: bR3EOtSngkb9wNbixylsw0sNa_2HCga5
sequenceReference:
id: refseq:NP_009225.1
name: NP_009225.1
description: The protein product of the MANE Select (GRCh38) coding transcript for BRCA1 (refseq:NM_007294.4), corresponding to the Refseq protein accession NP_009225.1.
aliases:
- ensembl:ENSP00000350283.3
- ga4gh:SQ.nUzIPnHMyQV52hzgBbKl5vlbSwx8M8_Y
type: SequenceReference
refgetAccession: SQ.nUzIPnHMyQV52hzgBbKl5vlbSwx8M8_Y
residueAlphabet: aa
start: 1852
end: 1853
sequence: Y
state:
type: LiteralSequenceExpression
sequence: '*'
relations:
- primaryCoding:
code: translation_of
system: http://www.sequenceontology.org
iris:
- http://www.sequenceontology.org/browser/current_release/term/translation_of
mappings:
- coding:
system: https://www.ncbi.nlm.nih.gov/clinvar
code: '55628'
iris:
- https://www.ncbi.nlm.nih.gov/clinvar/variation/55628/
relation: exactMatch
- coding:
system: https://reg.clinicalgenome.org/
code: CA003713
iris:
- https://reg.clinicalgenome.org/redmine/projects/registry/genboree_registry/by_caid?caid=CA003713
relation: relatedMatch
- coding:
system: https://www.ncbi.nlm.nih.gov/snp
code: rs80357629
iris:
- https://www.ncbi.nlm.nih.gov/snp/rs80357629
relation: relatedMatch
members:
- id: ga4gh:VA.ju31SHNY7xeTI244BcOS7J78dIek46xL
type: Allele
name: NC_000017.11:g.43045712dup
description: VRS variation of NC_000017.11:g.43045712dup, generated with the VICC Variation Normalizer (https://github.com/cancervariants/variation-normalization).
digest: ju31SHNY7xeTI244BcOS7J78dIek46xL
expressions:
- syntax: hgvs.g
value: NC_000017.11:g.43045712dup
- syntax: hgvs.g
value: NC_000017.10:g.41197729dup
- syntax: hgvs.c
value: NM_007294.4:c.5558dup
- syntax: hgvs.p
value: NP_009225.1:p.Tyr1853Ter
location:
id: ga4gh:SL.El1CbTY3p0rvxxkf5qI3YdgTo46YIjwl
description: Genomic position 43,045,712 on chromosome 17 (refseq:NC_000017.11, GRCh38).
type: SequenceLocation
extensions:
- name: GRCh38 1-based, genomic position
value: chr17:43045712
description: Genomic position 43,045,712 on chromosome 17 (refseq:NC_000017.11, GRCh38).
- name: GRCh38 1-based, inclusive interval notation
value: chr17:43045712-43045712
description: Genomic positions 43,045,712 to 43,045,712 on chromosome 17 (refseq:NC_000017.11, GRCh38); 1-based, inclusive interval notation.
- name: GRCh38 0-based, half-open interval notation
value: chr17:43045711-43045712
description: Genomic positions 43,045,711 to 43,045,712 on chromosome 17 (refseq:NC_000017.11, GRCh38); 0-based, half-open interval notation.
digest: El1CbTY3p0rvxxkf5qI3YdgTo46YIjwl
sequenceReference:
id: refseq:NC_000017.11
name: NC_000017.11
description: Reference sequence for GRCh38 chromosome 17
type: SequenceReference
refgetAccession: SQ.dLZ15tNO1Ur0IcGjwc3Sdi_0A6Yf4zm7
residueAlphabet: na
start: 43045711
end: 43045712
sequence: T
state:
type: ReferenceLengthExpression
length: 2
sequence: TT
repeatSubunitLength: 1
- id: ga4gh:VA.UPNFCFuk1_6v7IzYbbQTV_PsYJ9WOwSa
type: Allele
name: NC_000017.10:g.41197729dup
description: VRS variation of NC_000017.10:g.41197729dup, generated with the VICC Variation Normalizer (https://github.com/cancervariants/variation-normalization).
digest: UPNFCFuk1_6v7IzYbbQTV_PsYJ9WOwSa
expressions:
- syntax: hgvs.g
value: NC_000017.11:g.43045712dup
- syntax: hgvs.g
value: NC_000017.10:g.41197729dup
- syntax: hgvs.c
value: NM_007294.4:c.5558dup
- syntax: hgvs.p
value: NP_009225.1:p.Tyr1853Ter
location:
id: ga4gh:SL.bJxQ_soqGHGy4skIMKp6VLEB54XH32M8
description: Genomic position 41,197,729 on chromosome 17 (refseq:NC_000017.10, GRCh37).
type: SequenceLocation
extensions:
- name: GRCh37 1-based, genomic position
value: chr17:41197729
description: Genomic position 41,197,729 on chromosome 17 (refseq:NC_000017.10, GRCh37).
- name: GRCh37 1-based, inclusive interval notation
value: chr17:41197729-41197729
description: Genomic position 41,197,729 to 41,197,729 on chromosome 17 (refseq:NC_000017.10, GRCh37); 1-based, inclusive interval notation.
- name: GRCh37 0-based, half-open interval notation
value: chr17:41197728-41197729
description: Genomic position 41,197,728 to 41,197,729 on chromosome 17 (refseq:NC_000017.10, GRCh37); 0-based, half-open interval notation.
digest: bJxQ_soqGHGy4skIMKp6VLEB54XH32M8
sequenceReference:
id: refseq:NC_000017.10
name: NC_000017.10
description: Reference sequence for GRCh37 chromosome 17.
aliases:
- GRCh37:17
- GRCh37:chr17
- ga4gh:SQ.AjWXsI7AkTK35XW9pgd3UbjpC3MAevlz
type: SequenceReference
refgetAccession: SQ.AjWXsI7AkTK35XW9pgd3UbjpC3MAevlz
residueAlphabet: na
start: 41197728
end: 41197729
sequence: T
state:
type: ReferenceLengthExpression
length: 2
sequence: TT
repeatSubunitLength: 1
- id: ga4gh:VA.BfZ-RbjStWkafMsFBcoSL0f4aAjHJU4n
type: Allele
name: NP_009225.1:p.Tyr1853Ter
description: VRS variation of NP_009225.1:p.Tyr1853Ter, generated with the VICC Variation Normalizer (https://github.com/cancervariants/variation-normalization).
digest: BfZ-RbjStWkafMsFBcoSL0f4aAjHJU4n
expressions:
- syntax: hgvs.g
value: NC_000017.11:g.43045712dup
- syntax: hgvs.g
value: NC_000017.10:g.41197729dup
- syntax: hgvs.c
value: NM_007294.4:c.5558dup
- syntax: hgvs.p
value: NP_009225.1:p.Tyr1853Ter
location:
id: ga4gh:SL.bR3EOtSngkb9wNbixylsw0sNa_2HCga5
description: Amino acid position 1853 of the Refseq protein NP_009225.1, which is the protein product of the MANE Select (GRCh38) coding transcript for BRCA1 (refseq:NM_007294.4).
type: SequenceLocation
digest: bR3EOtSngkb9wNbixylsw0sNa_2HCga5
sequenceReference:
id: refseq:NP_009225.1
name: NP_009225.1
description: The protein product of the MANE Select (GRCh38) coding transcript for BRCA1 (refseq:NM_007294.4), corresponding to the Refseq protein accession NP_009225.1.
aliases:
- ensembl:ENSP00000350283.3
- ga4gh:SQ.nUzIPnHMyQV52hzgBbKl5vlbSwx8M8_Y
type: SequenceReference
refgetAccession: SQ.nUzIPnHMyQV52hzgBbKl5vlbSwx8M8_Y
residueAlphabet: aa
start: 1852
end: 1853
sequence: Y
state:
type: LiteralSequenceExpression
sequence: '*'